SYNENTEC NyONE Compact Cell Imager

SYNENTEC provide the most versatile cell imagers on the market.The NyONE automated microscope is compatible with a wide range of SBS format plate types, having a small footprint makes it easy to install in any lab. Data analysis is via SYNENTEC’s inbuilt powerful image processing tools which gather robust data and are simple to use with a variety of configurable data export options.

Applications include:

  • Single Cell Cloning (SCC)
  • Fluorescence Activated SCC (FASCC)
  • Confluence monitoring
  • Transfection Efficiency
  • Cell Counting/viability
  • Antibody Quantification & glycan analysis – PAIA
  • Cell Apoptosis Monitoring
  • Virus Quantification
  • iPS Cell Monitoring
  • Viral Transduction
  • Toxicity Studies
  • Wound Healing assays

In addition the new NyONE scientific option is specifically targeted at cancer research and drug discovery applications bringing both high content and high throughput applications to your lab.The 16bit sCMOS camera platform offers exceptional image quality/sensitivity whilst the harmonic motor drives for plate handling are optimised to minimise disturbance to your cells resulting in wonderfully clear images.

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More on SYNENTEC

SYNENTEC provide the most versatile cell imagers on the market. The instruments all have the option of full fluorescence capability. This means that the applications range from single cell cloning, apoptosis studies, through to transfection efficiency, toxicity studies and ultra-high throughput cell counting with viability. The instruments are compatible with a wide range of SBS format plate types and have a built in automation interface enabling integration into CLD platforms.

SYNENTEC’s team of engineers, software developers and biologists have developed automated, high throughput cell culture microscopes and fast, easy to use image analysis software.

The Cellavista, a high throughput fully automated cell imager, was launched in June 2007 and has been continuously developed ever since and was joined by the NyONE range of instruments in 2014. The instruments are used throughout the industry for applications varying from single cell cloning through to apoptosis studies.

Ellen’s take on this product

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Ellen Harrington
Technical Sales Specialist

Versatile: Time saved by automation combined with precision optics and a wide range of applications make these imagers an integral part of any CLD workflow. Both extremely robust, the Cellavista offers higher throughput and is perfect for automated environments, while the smaller NyONE is ideal for medium-throughput laboratories with limited bench space. An extensive range of applications within Cell Line Development, Vaccine Research, Drug Discovery, Cancer Research, Stem Cell Studies and others makes these imagers the ultimate cell culture instrument.

Innovative: SYNENTEC are constantly developing new applications to meet the needs of customers. Technical assistance provided by the SYNENTEC team as well as local applications training means the user is supported from day 1.

Did you know?

For customers working in cGMP environments, SYNENTEC have developed YT AUDIT, a validation software which meets requirements for CFR21 part 11 compliance.

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    Advantages

    • Combines the advantages of a high end plate imager with a smaller footprint, at a reduced cost compared to the Cellavista Cell Imager
    • Impressive imaging speed – runs a complete scan of a 96-well microplate in 5 minutes
    • Equipped with 3 different lenses, achieving resolutions down to 360 nm/pixel, 4 different excitation sources (UV to RED) and up to 6 different emission filters
    • Ultrafast filter wheel – 40ms position changing time. Well suited for FRET assays
    • Achieve extraordinary image quality using specifically designed optic and laser autofocus mechanisms
    • Perform automated, high quality image analysis in parallel with image acquisition

    For full a list of applications and technical notes, please visit SYNETEC’s website

    SCIENTIFIC Technical Specifications:

    CLD Technical Specifications:

    NYONE – Comparisons between Scientific and CLD

    Scientific

    Cell Line Development

    Fluorescent Channels

    4

    Optional (Up to 4)

    Measurement Time at 4x

    96 Well

    3 minutes

    4 minutes

    384 Well

    4 minutes

    6.5 minutes

    Magnification

    4x

    Optional

    10x

    20x

    Optional

    40x

    Optional

    Optional

    High NA

    Optional

    Harmonic Drive

    Pixel Density

    2048 x 2048

    2048 x 2048

    Digital output

    8 or 16 bit

    8 bit

    SYNENTEC provide the most versatile cell imagers on the market.

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