Elevate your cell line development workflow

The UP.SIGHT streamlines cell line development (CLD) workflows by automating labor-intensive and time-consuming steps. CYTENA have combined their patented, highly efficient, fast and gentle single-cell dispensing technology with a fast, high-quality imaging system that provides a full well image.

The UP.SIGHT combines nozzle imaging and 3D Full Well Imaging for double assurance of clonality from two independent optical apparatuses, leading to a probability of clonality >99.99%.


Higher yields, greater insights, faster processing

The UP.SIGHT combines CYTENA’s patented single-cell dispensing technology with a powerful imaging system for an improved single-cell cloning workflow, enabling higher clonal yields and processing hundreds of clones in under 30 minutes.

Click to view larger image

Double assurance of clonality

The UP.SIGHT offers two independent methods of assuring monoclonality;

  • First, images are taken at the dispensing nozzle to ensure only one cell is placed in each well, and nonclonal droplets are discarded.
  • Second, the single cells are confirmed once more with 3D Full Well Imaging, a new and innovative method that images the full volume of each well from the point of dispensing using the integrated imager.
  • Probability of clonality >99.99%

More on CYTENA

CYTENA is the leader in single-cell printing. Their patented, single cell printing technology enables fully automated isolation of single cells, with user friendly software with multiple applications including cell line development, single cell genomics and R&D. The cytena single cell printer (SCP) technology presents, for the first time, documented proof of clonality and provides efficient and fast single cell seeding combined with excellent cell viability.

Ellen’s take on this product


Ellen Harrington
Technical Sales Specialist

Uncomplicated: This range of single cell printers (C.SIGHT, F.SIGHT, B.SIGHT and UP.SIGHT) feature CYTENA’s patented single cell dispensing technology which quickly and efficiently deposits single cells while discarding droplets with zero or multiple cells. This method of discarding unsuitable droplets prior to dispensing allows for substantial time savings and higher probability of single cells, while saving plate space.

Thorough: Nozzle images taken at the time of dispensing provide proof of clonality. For double assurance of clonality, the UP.SIGHT was developed which combines CYTENA’s trusted dispensing technology with a high quality imaging system to provide 3D full well imaging. The UP.SIGHT’s extra assurance of clonality is beneficial for meeting regulatory requirements and also allows for subsequent monitoring of colony outgrowth.

Did you know?

C.BIRD – for cell lines that require suspension mixing, the C.BIRD microbioreactor replaced the traditional static growth stages with a mixed environment for optimum cell quality and product yield.


    Minimising cell loss

    Add an additional layer of optimization with Cell Focusing technology, which gently aligns cells at the center of the dispensing cartridge for superior cell detection. It offers significant improvements when working with rare cell types by ensuresing that cells are perfectly captured and measured, reducing cell loss and increasing processing speeds.

    Featured workflow

    CYTENA’s extensive product portfolio offers a range of innovative technologies and instruments for significantly increasing the speed, quality and efficiency of your cell line development workflows.

    Tool free, single-use cartridge

    The UP.SIGHT’s exclusive EASY.ON cartridge is precisely engineered by microfluidic experts to ensure cell viability with the gentlest handling and is disposable to eliminate the risk of cross-contamination between samples. Plus, setting up your experiments has never been easier as the EASY.ON cartridge is magnetically mounted for quick and easy loading.

    CYTENA is the leader in single-cell printing.