PRODUCTS

Carr Centritech

The Carr Centritech range of bioprocessing equipment is the most extensive of its kind, offering the industry's only complete family of centrifuge solutions. – everything from bottles to continuous flow.


By bringing together three of the industry's leading brands - SORVALL®, Heraeus® and Carr® - Carr Centritech can take you from basic reaearch to pilot through to production easily without extensive rework of your process, achieving virtually any kind of separation from recombinant proteins to vaccines to plasma fractionation.

BioProcess Engineering Services Ltd. have worked with Carr Centritech in the UK & Ireland since 1997 acting as a full exclusive distributor for the pilot scale systems and as an agent for all the larger scale production systems.

The Range


Large Particles – Mammalian, Human, Insect & Plant Cells.

Centritech®

Gentle separation/perfusion system working at up to 250 x g. Two systems are available – Centritech® CELL and Centritech® LAB-II.

Benefits

  • Ergonomic design suited to modern laboratory environments
  • Gentle cell handling coupled with dead cell removal offers higher viability and productivity.
  • Closed system with pre-sterilised disposable inserts.
  • Need for CIP/SIP Eliminated
  • Automated continuous separation
  • Fully scalable with 5-3000 Litre perfusion bioreactors or 5-600 Litre cell harvesting.

 

 
 

Viafuge®
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The CARR® Viafuge® range of separation systems designed for small to large scale cell harvesting and supernatant recovery. Capable of separating a wide variety of mammalian and insect cells with little or no damage, The Viafuge® offers intact cell recovery efficiencies in excess of 99% with non-detectable cell concentrations in clarified supernatant.

Benefits

  • Due to gentle recovery and minimal cell damage, up to 90% reduction in downstream process filtration requirements.
  • Unique SoftStream® low shear design, Feed is matched to bowls rotational velocity, allowing fast efficient harvesting of even the most shear sensitive of cells without causing damage.
  • Feed rates from 0.1 – 40 L/min*
  • Cells can be concentrated by a factor of 30 for the Pilot scale machine and 20 for the V12 production scale machine.
  • Closed system design – Concentrated cells and supernatant can be recovered without breaking containment.
  • Fully Automated CIP/SIP option available.
  • Integrates easily into automated processes.

*Actual flow rates are dependent on the characteristics of the fluid, amount and type of solids and required degree of clarification.

Small Particles – Bacteria, Yeast, Large subcellular components & Plasma Proteins.

 
 

Powerfuge®
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Powerfuge® is a scalable family of high-efficiency separation systems operating from 500 to 20,000 x g. Four systems are available- Pilot, P6, P12 & P18 operating with flow rates from 10 – 1,700 Litres per hour and solids capacity from 1 to 36 Kg per cycle.

Benefits

  • Fully scalable.

  • Higher product recovery through more complete liquid/solid separation.

  • True Clean® design enables cGMP compliance by way of sanitary design with integrated CIP/SIP software programs.(P6, P12 & P18)
  • Closed system design – Solids and supernatant can be recovered without breaking containment. (P6, P12 & P18) Pilot scale machine can be operated in a laminar flow cabinet)
  • Integrates easily into automated processes
  • Extensive options available including CIP Skid, Full automation & 2 bar SIP.

 

Ultra-Small Particles – Viruses, Proteins & small subcellular components

 

TCF-32®
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The TCF-32 continuous flow Rotor operated in the Discovery series of Ultracenrifuges provides one-step processing of pilot-scale samples at speeds of up to 32,000 rpm, RCF to 102,000 x g and flows rates of up to 9 L/hr with a maximum volume of 940ml.

SORVALL® CC40
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Achieving large-scale isolation or purification of viruses and proteins typically involves trade-offs, expensive consumables, large space requirements and noise discomfort. The CC40 from SORVALL® offers a new approach that's easy, reliable and proven and imposes no such drawbacks.

Benefits

  • High Throughput batch processing – processes up to 200L continuously.
  • Minimal Footprint, more location flexibility – No need for a separate air turbine compressor.
  • Microcomputer Control – Automatic microcomputer digital control simplifies operation . Providing digital display of rotor speed, time, temperature and vacuum state.
  • Unattended Operation – High reliability and automatic error detection enable walk-away operation.
  • Quiet Operation – Ambient noise is only 75dB at 40,000 rpm.
  • Configuration flexibility – choose from a variety of rotors and accessories including an optional sample feed subsystem.
  • EMC & CE compliance – Full compliance with all relevant US and European standards.
 
     
  All information contained on this website is correct to the best of our knowledge – every effort will be made to keep the information up to date.